Wilkins Sound is a seaway in Antarctica that is largely occupied by the Wilkins Ice Shelf. It is located on the southwest side of the Antarctic Peninsula between the concave western coastline of Alexander Island and the shores of Charcot Island and Latady Island farther to the west. Its northern portion was first seen and roughly mapped in 1910 by the French Antarctic Expedition under Jean-Baptiste Charcot and was observed from the air in 1929 by Sir Hubert Wilkins.