Holdrege station is an Amtrak intercity train station in Holdrege, Nebraska, served by the California Zephyr. It was originally opened in February 1911 by the Chicago, Burlington and Quincy Railroad as the CB&Q Holdrege Depot, and the depot has been listed on the National Register of Historic Places since February 21, 1997. However, the depot is no longer part of the station facilities.